The overall safety and PD profiles of tirzepatide in Japanese participants were comparable with other phase 2 studies in non-Japanese participants with T2D. 2. Tirzepatide is a GIP receptor and GLP-1 receptor agonist, leading to significantly improved glycemic control in type 2 diabetics and significant weight reduction. 6 kg with placebo [57]. And if dehydration is severe enough, it could cause kidney damage. Tirzepatide is administered through subcutaneous injection (under the skin). 2mg X 10 Vials. 2. In clinical trials, tirzepatide has produced the following weight loss results:Tirzepatide is a new medication that was approved in May 2022 for Type 2 diabetes. Buy 10 for $139. The overall average weight reduction for the highest dose of tirzepatide (15 mg) was about 52 pounds. 1 million people in Japan have impaired glucose tolerance. I have been using Saf-Research tirzepatide. Tirzepatide, the active ingredient in the diabetes medication. 5mg per week that would equate to 12 weeks x 2. You would get a vial of dry peptide then have to reconstitute it yourself and figure the dosage yourself instead of the pharmacy doing it for you. Given its potent weight loss properties, tirzepatide be used off-label for obesity treatment. Tirzepatide is a synthetic linear peptide with agonist activity at both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). Anthony Jay Millard, a weight loss specialist from the Northwestern Medicine Center for Lifestyle Medicine, Mounjaro is the brand name for the drug tirzepatide, which is currently. But it’s also showing promising results in studies for people. 5ml aliquot will be 2. Maximum dose: 15 mg subcutaneously once a week. As such, advanced treatment approaches are needed. All three medications are once weekly. Introduction and background. 2,539 adult clinical trial showed weight loss from 15% to 35% weight loss versus placebo group. humans as the human relevance of tirzepatide-induced . • 10 mo. Tirzepatide (Subcutaneous Route) Tirzepatide injection is used to treat type 2 diabetes. This medicine is available only with your doctor's prescription. The efficacy. It is not intended for human consumption, medical, or therapeutic use – we will not provide any instruction pertaining to such uses. You can see this in Mounjaro trials documentation. Its association with cardiovascular outcomes requires evaluation. *Bulk discount will be displayed in your shopping cart. kidney problems --little or no urination, swelling in your feet or ankles, feeling tired or short of breath. 5 mg per week = 8 doses. 5mg/weekly in weeks 9-12, 10mg/daily in weeks 13-16, 12. We observed that the effect of. How is tirzepatide administered and what are the available doses? •Tirzepatide is administered once weekly by subcutaneous injection using a single-dose prefilled auto- injector pen with a pre-attached hidden needle. 81kg) weight loss (average of the 5mg, 10mg, and 15mg/weekly results) compared to placebo. Tirzepatide is a combination of two drugs that work together to regulate blood glucose levels in a new and innovative way. Its association with cardiovascular outcomes. QUICK TAKE Once-Weekly Tirzepatide for Obesity 01:48. Background: Despite advancements in care, many people with type 2 diabetes do not meet treatment goals; thus, development of new therapies is needed. Tirzepatide. Buy Tirzepatide Online. For laboratory use by qualified professionals. If needed, dose increases can be made in 2. The type 2 diabetes drug tirzepatide (better known by its brand name Mounjaro) has recently been authorised by the UK’s medicines regulation authority for use in weight loss and weight management. One tirzepatide trial in people without diabetes showed volunteers taking the highest dose, 15 mg a week, lost as much as 27% of their body weight, which is comparable to or more than the weight. Tirzepatide is dosed at 5-15mg per week. Tirzepatide, known as a ‘twincretin’, is a ‘first-in-class’ and the only dual glucagon-like peptide-1 (GLP-1) and glucose-dependent. 1%, 6. Only really lost significant weight (20lbs) the first month. 5 mg, 7. Of interest to payers: many more patients taking tirzepatide had adverse events that caused them to stop taking the drug; 28 at the 5 mg dose, and 40 each at 10 mg and 15 mg; only 19 patients. In clinical practice, tirzepatide and semaglutide. But most insurance plans cover the medication when it’s prescribed to treat Type 2 diabetes. , when it was taken at its highest dose in a drug trial. Come 2030, Cowen expects Novo’s Wegovy sales to top $7 billion, while its full obesity portfolio could reach $14. GI Side Effect Mitigation: Gradual dose escalation can minimize gastrointestinal side effects like nausea and constipation. 5% Pure Click Here to See Full Certification of Analysis Tirzepatide is a synthetic analogue of gastric inhibitory polypeptide (GIP) that was. Azithromycin 6 tablets of 250mg, 1 z-pak. tirzepatide (20mg) is shown to lead to approximately 20% body weight loss. Adverse events caused treatment discontinuation in 4. 5mg. Despite tirzepatide’s promising results, it has researchers puzzled. After 4 weeks, increase the dose to 5 mg once weekly. My question is, if I'm on 2. Order in bulk and SAVE! Order: 5 – 9 vials and SAVE 10%. Tirzepatide is a dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) approved by the US Food and Drug. You can email them at mtoyos@toyosclinic. The purified tirzepatide–GIPR–G s –Nb35 complex at a concentration of 18-20 mg/mL was mixed with 100 μM tirzepatide at 4 °C and applied to glow-discharged holey carbon grids (Quantifoil R1. While tirzepatide may potentially be more effective, it's too early to know that based on current research. Proper Use. What's important is when to increase your dose, how often you increase the dose, and when to dose the medication. This combination allows Tirzepatide to lower blood glucose levels, increase insulin sensitivity, boost feelings of satiety, and accelerate weight loss. . Like I said, a 10 mg vial is 10 mg, no matter how much water you add. The Net Peptide Content (NPC) of current batch (MTFA30421-0830) is 91. Participants received a starting. 28%,The therapeutic dose for Ozempic is 0. 81kg) weight loss (average of the 5mg, 10mg, and 15mg/weekly results) compared to placebo. Participants received a starting. 5 mL. Tirzepatide is a synthetic analogue of gastric inhibitory polypeptide (GIP) that was developed for its ability to stimulate insulin release and thus address both type 2 diabetes and non-alcoholic fatty liver disease. The pooled analysis revealed that tirzepatide led to -21. 07% with 15 mg of tirzepatide. 00 – $ 799. S. Native GIP and GLP-1 are incretin hormones that stimulate insulin secretion and decrease glucagon secretion. 1 percentage points (with the 15 mg dose), compared to no change in the placebo group. In Eli Lilly's SURMOUNT-1 clinical trial, its experimental obesity drug—a weekly injection called tirzepatide—helped clinical trial patients lose roughly one-fifth of their body weight. It is unknown whether MOUNJARO causes thyroid C-cell . 87% with 5 mg of tirzepatide, -1. At baseline, the mean glycated hemoglobin level was 8. 813-333-2226. People taking it tend to lose weight. Tirzepatide is a novel, once weekly, dual GIP/GLP-1 receptor agonist and is under development for the treatment of type 2 diabetes (T2D) and obesity. 0 mg per week = 2 doses ** Derby City Direct Primary Care members will received a discount of $50 per month on Tirzepatide medication. Weeks 9-12: One Vial of 30mg Mounjaro Injections (Tirzepatide) Inject 7. These tumors were only seen in animal studies of. Semaglutide to Tirzepatide Conversion. Inject 2. Tirzepatide is a first-in-its-drug-class medication for type 2 diabetes. 813-333-2226. Specifically, tirzepatide at 10 mg reduced body weight by 5% or more in 79. In fact, scientists have long thought that. It has a role as a glucagon -like peptide-1 receptor agonist. At a maintenance dose of 2. Å = Aib, alpha-amino-butyric acid; diacid-γ-Glu(AEFA)2, the linker molecule linking a fatty acid side chain with a length. 5, 5, 7. The primary end point was percentage change in body weight from baseline to week 72. 5 mg once-weekly and then increased the dose in a step-wise approach at four-week intervals to their final randomized maintenance dose of 5 mg (via a 2. Get free coupon. Tirzepatide showed a 21% decrease in body weight over 72 weeks on the 15 mg dose vs 3% in the placebo arm which is a difference of 41. Participants receiving tirzepatide had a total mean weight reduction of 24. 5mg. Tirzepatide Tizanidine Topiramate Ulipristal Valproic Acid Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. humans as the human relevance of tirzepatide-induced . Those taking 10mgs. Fax: 813-463-7830Another weight loss medication designed to treat diabetes is part of a promising class of new drugs that may aid weight loss. 5% for the 10mg dose, 20. At 40 weeks, a significant reduction in HbA1c proportional to the dosage of the drug used was observed (-1. 5. 1. Eli Lilly & Company will. 5mg/weekly for the first four weeks of the study period, followed by an increase to 5mg/weekly in weeks 5-8, 7. The mean age of participants was 45 years, with 69% female and 71% white. 5mg per week and increases based on the patient’s response. It’s clear how GLP-1 helps to spur weight loss, but GIP’s role is a surprise. 12To qualify for Lilly’s trial, participants had to lose at least 5% of their body weight by the end of the 12-week lead-in. This copyrighted material has been downloaded from a licensed data provider. Tirzepatide injection is used to treat type 2 diabetes. Tirzepatide Lyophilized Powder. The FDA has approved tirzepatide (Mounjaro; Eli Lilly and Company), a novel, dual-targeted treatment shown to improve glycemic control in adults with type 2 diabetes. Special-Buffalo-5114 • 6 mo. 5-2. Tirzepatide is a novel diabetes medication that has been approved by the Food and Drug Administration (FDA) []. 7 or 2. 1 Excess adiposity and its numerous. 4% and 15. Based on the above protocol and our preferred vendor's current pricing, here is a breakdown of the total cost per dose on a weekly basis: Weeks 1-4: $82. The Tirzepatide group also had improved cardiovascular and metabolic measures. The authors found that tirzepatide 15 mg was the most efficacious in reducing HbA1c versus placebo (mean difference -2. 1). Doses of 500mcg or more can be injected with one ml of water. Clinical trials have shown that tirzepatide may result in weight reductions of 15% to 25% in individuals receiving the highest dose of 12 mg. SKU: SR-TIRZ Categories: Peptides, USA Peptide Only Tags: Peptide, Peptides, Tirzepatide, USA Peptides. Tirzepatide is a combination glucagon-like peptide 1 (GLP-1) receptor AND glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. Novo also has an oral semaglutide and three other candidates in its pipeline. Fax: 813-463-7830Tirzepatide is a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist approved for type 2 diabetes. 4% and 15. 1% for placebo. 00 — or Auto-refill and save up to 10% Select options; Gift Card $ 50. Tirzepatide. 4mg. Tirzepatide is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Tirzepatide is a novel medication that is FDA approved for the treatment of type 2 diabetes mellitus. 59) and diarrhea (OR 3. 25mg per week and increases weekly, based on the patients’ response. We aimed to assess efficacy, safety, and tolerability of novel dual glucose-dependent insulinotropic polypeptide and GLP-1 receptor agonist tirzepatide monotherapy versus placebo in people with type 2 diabetes inadequately controlled by diet and. The Tirzepatide weight loss study, called SURMOUNT-1, evaluated the efficacy and safety of Tirzepatide for weight loss in obese individuals. It's not clear to others because you don't understand it yourself. Other names: Tirzepatide raw powder, Mounjaro, LY-3298176, CHEBI:194186, Tirzepatide’s weight loss efficacy is supported by clinical trials. TIRZEPATIDE PEPTIDE 5MG/10MG VIAL. It is not known if this happens in humans. 5mg with the 10mg bottle, add 2ml of bac water and draw up 0. This is where Tirzepatide comes in. In addition to mimicking GLP-1, tirzepatide mimics another gut hormone called gastric inhibitory polypeptide, or GIP, that scientists believe has a similar effect on the body as GLP-1. 5mg would equate to 18. It works by increasing insulin available and decreasing glucagon (a hormone that controls the amount of glucose made by the liver) available in the body. 01 to 2. Featured. 32% with 10 mg and 5. 8, 2023 /PRNewswire/ -- The U. It works to stimulate first- and second-phase insulin secretion, and reduces glucagon levels, both in a glucose-dependent manner. ReviveRX is committed to ensuring that our compounded medications are safe, effective, and meet the highest quality standards. It is a 39-amino-acid modified peptide based on the GIP sequence. 87% with 5 mg of tirzepatide, -1. of tirzepatide at 5 mg, 10 mg, or 15 mg or placebo along with lifestyle modification. S. 4 milligrams weekly. Tirzepatide is a therapeutic medicine, an acylated peptide that many refer to by its brand name, Mounjaro. The peptide also led to significantly. It is currently. Tirzepatide is available in multiple strengths (2. Decrease Cravings: Helps in reducing cravings for sweet, salty, and fatty foods. Weeks 9-12: 5 mg for four weeks, once a week (20mg total peptide). Data from the SURMOUNT-2 trial suggests use of tirzepatide (Mounjaro) was associated with superior. It is estimated that 7. It is used together with diet and exercise to help control your blood sugar. Pharmaceutical experts classify Tirzepatide as an anti-diabetic drug that experts. The current focus areas for research are preventative factors to combat accelerated β-cell deterioration - a critical cause of diabetes - and exploring the benefits. Adding 50 units would be fine. 7. You will be taught how to prepare and give it. Tirzepatide, brand name Mounjaro, is a new prescription medication for weight loss and type 2 diabetes management. The efficacy and safety of tirzepatide 5, 10 and 15 mg have been extensively investigated in the phase 3 SURPASS programme in various populations along the continuum of T2D management. or 13. Tirzepatide $ 699. I’m on 20mg Vyvance 300MG XR BUPROPION and 2. Years ago, I used to take 10mg IR twice daily, but it felt way too intense and I’d always forget to take the 2nd pill in the afternoon (because ADHD). This distinction is required on the labels of research chemicals, and is what exempts them from regulation under parts 100-740 in Title 21 of the Code of Federal Regulations (21CFR). In Eli Lilly's SURMOUNT-1 clinical trial, its experimental obesity drug—a weekly injection called tirzepatide—helped clinical trial patients lose roughly one-fifth of their body weight. tumors, including medullary thyroid carcinoma (MTC), in . 5 mg once-weekly and then increased the dose in a step-wise approach at four-week intervals to their final randomized maintenance dose of 5 mg (via a 2. tirzepatide 10 mg/0. Participants lost an average of 15-21 pounds on the 5 mg. 00 — or Auto-refill and save up to 10% Select options; NAD+ InjectionsObjective Tirzeptide is a novel glucagon-like peptide-1 receptor (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) drug, which shows good efficiency for weight loss. It's not clear to others because you don't understand it yourself. Monotherapy tirzepatide lowered HbA 1c by 2·07% (23 mmol/mol) and bodyweight by 9·5 kg from a baseline of 7·9% (63 mmol/mol). It is the first of its kind to act as a dual-acting glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist [2,3]. Tirzapatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. (15. Tirzepatide (Mounjaro™) is a single molecule that combines dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. Buy 10 for $139. 8 lb. All participants in the tirzepatide treatment arms started the study at a dose of tirzepatide 2. 7% (34. At what dose is tirze This medication is injected under the skin. I was wondering about purity so I had mine tested in a lab in Arizona and it came back 99. Get free coupon. 5. At 40 weeks, a significant reduction in HbA1c proportional to the dosage of the drug used was observed (-1. The dosages used in the study were escalated over the first 12 weeks of the trial. It works as a dual GLP-1 agonist and GIP agonist to maximize similar benefits that are seen with GLP-1 medications such as semaglutide. •In rats, tirzepatide causes thyroid C-cell tumors. 28. 9% weight reduction) by week 12 and were included in the tirzepatide. 99 each and save 12%. • Tirzepatide causes thyroid C-cell tumors in rats. Tirzepatide was approved as Mounjaro ® (tirzepatide) by the FDA on May 13, 2022. Tirzepatide injection is used to treat type 2 diabetes. Tirzepatide - Here is the protocol and dosing for Tirzepatide “I” follow: Weeks 1-4: 2. Description. Hello- I need help!Tirzepatide is a once-weekly dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that integrates the actions of both incretins into a single novel molecule. Weeks 1-4: One Vial of 10mg Tirzepatide +. and 15 mg of tirzepatide, respectively, and 35% (95% CI, 30 to 39) with placebo; 50% (95% CI, 46 to 54) and 57% (95% CI, 53 to 61) of participants in the 10-mg and 15-mg groups had a reduction in. In study participants with a BMI≥ 27 kg/m2 and T2D, tirzepatide 10 mg and 15 mg once weekly doses reduced body weight by 12·8% and 14·7%, respectively, vs. under the brand name Mounjaro™ and was approved in May 2022. 5mg is half the drug in the vial, so however much you reconstitute with, a 2. This translates into 1800mcg which in turn would mean 1. tirzepatide 10 mg/0. 7%) of body weight with 10 mg and 15 mg of tirzepatide (Mounjaro; Eli Lilly and Company), according to findings. 4 pounds (15. 00 – $ 599. 7% of patients and decreased average. 12 to 10. Fax: 813-463-7830Tirzepatide (TZP) is an imbalanced agonist of the GIP and GLP-1 receptors and shows biased pharmacology at the GLP-1 receptor. Tirzepatide (Mounjaro) is a glucose-dependent insulinotropic polypeptide- and glucagon-like peptide-1 receptor agonist indicated to improve blood sugar control in adults with type 2 diabetes. Semaglutide is dosed at 0. *OUR PRODUCTS ARE NOT DIETARY SUPPLEMENTS OR MEDICATIONS. 1, 13. 2% of patients and reduced average body weight by 12. Tirzepatide, sold under the brand name Mounjaro among others, is an antidiabetic medication used for the treatment of type 2 diabetes and for weight loss. What does tirzepatide cost? As of right now, GoodRx says that tirzepatide costs in the mid-$900 to about $1,200 range for four pens without health insurance. 9% for the 15mg dose, and 3. Amoxicillin 500mg, 21 capsules. 3 kg) in patients with T2DM. INDIANAPOLIS, Nov. 5, 10, 12. In the phase 1 and phase 2 trials tirzepatide demonstrated dose-dependent reduction in HbA1c (up to 2. Tirzepatide, −7. This product requires monthly dosing step-up. ago. 5 mg for four weeks, once a week (14mg total peptide). 5mg, and 15mg) as a once weekly subcutaneous injection that involves titration to the appropriate dose. 5 mg is the amount B6 per 0. S. 4 mL X 4 Injections Month 3 Dosing: Tirzepatide / BPC157/B6 7. 00%), followed by tirzepatide 10 mg (-1. 4-mg dose and tirzepatide up to a 15-mg dose, focusing on the Semaglutide Treatment Effect in People with Obesity (STEP) 2, SURPASS-1, and SURPASS-2 trials, the subjects of which were all patients with type 2 diabetes mellitus. 0 or 2. It works by. 2 out of 10 from a total of 594 ratings on Drugs. The. Here are the key findings: Tirzepatide led to A1C reductions of 1. 00 — or Auto-refill and save up to 10% Select options; NAD+ Injections Three months is 12 weeks, so at 2. How much weight can I lose?Tirzepatide lose weight. INDIANAPOLIS, March 4, 2021 /PRNewswire/ -- Tirzepatide led to superior A1C and body weight reductions from baseline across all three doses compared to injectable semaglutide 1 mg in adults with type 2 diabetes in Eli Lilly and Company's (NYSE: LLY) 40-week SURPASS-2 clinical trial. 07% with 15 mg of tirzepatide versus +0. GLP-1 receptor agonists mimic the action of GLP-1 and help to regulate blood sugar levels in people with type 2 diabetes. Tirzepatide also. For example if you wanted to do 2. 89% with 20 mg of tirzepatide, and -2. 00 – $ 1,000. Tirzepatide is a novel medication that is FDA approved for the treatment of type 2 diabetes mellitus. Patients with obesity and type 2 diabetes (T2D) or with overweight and T2D lost an estimated 34. Please familiarize yourself with our Terms & Conditions prior to ordering. INFORMATION. The adverse drug reaction profile of tirzepatide is comparable to GLP-1 agonists, as it is a dual GIP/GLP-1 agonist. Here’s how the GLP-1 and GIP receptor agonist works, along with its potential benefits and side effects. 3% (7. The recommended dosing schedule for Tirzepatide is once weekly, at any time of day, with or without food. Amoxicillin 500mg, 21 capsules. 7%, respectively, with more than 80% of tirzepatide users achieving a body weight reduction of 5% or. Tretinoin 45g of 0. In the phase 1 and phase 2 trials tirzepatide demonstrated dose-dependent reduction in HbA1c (up to 2. 5 mg SC qWeek x 4 weeks initially; THEN increase to 5 mg SC qWeek. Tirzepatide is a dual-acting medication that works on your body’s natural GLP-1 (glucagon-like peptide) & GIP (glucose dependent insulinotropic polypeptide) receptors. 40 to 12. 5mg/week = 30mg. The prevalence of obesity and diabetes is an increasing global problem, especially in developed countries, and is referred to as the twin epidemics. Weeks 5-8: One Vial of 20mg Mounjaro Injections (Tirzepatide) Inject 5mg once a week. GIP is a hormone that may complement the effects of GLP-1. Tirzepatide Sale with 30% off from Peptide Pros, the Best USA SARMs and Peptides for Sale supplier since 2013. It contains two non-coded amino acid residues (Aib, α-amino isobutyric. S. 2 In. 00 – $ 599. Tirzepatide is a combination of two drugs that work together to regulate blood glucose levels in a new and innovative way. 5 mg, 10 mg, and 15 mg per 0. Revolutionary Weight Loss Peptide. $9. Get free coupon. — Tirzepatide has a novel dual GIP and GLP-1 receptor agonist mechanism of action and is seen as an add-on type 2 diabetes therapy; tirzepatide would achieve common thresholds for cost-effectiveness if priced between $5,500 – $5,700 per year —. Tirzepatide can bind to both the GIP and GLP receptors. 5 mg, 5 mg, 7. 0. 1mg x 10 Vials) 10mg (1mg x 10 Vials) IGF-1 LR3. It is a dual glucose -dependent insulinotropic polypeptide and glucagon -like peptide-1 agonist used for the management of type 2 diabetes mellitus. 5mg/weekly for the first four weeks of the study period, followed by an increase to 5mg/weekly in weeks 5-8, 7. 5ml. Tirzepatide treatment doses were escalated over an 8-week period to a final dose of 12 or 15 mg, which was administered during the remaining 4 weeks of the treatment period. 9%. Tirzepatide is a synthetic peptide with glucose-lowering effects. In addition, more participants achieved 5% or greater weight loss with both doses of tirzepatide than with semaglutide. All participants in the tirzepatide treatment arms started the study at a dose of tirzepatide 2. 8%-14. We’ve created a peptide dosage calculator to help you reconstitute your peptides fresh from the source, and then a peptide dosage chart with some common guidelines on dosing, timing, and injection site with all our sources and citations. 5 mg, 5 mg and 7. The SURMOUNT clinical development program is evaluating tirzepatide administered subcutaneously once weekly for CWM in people with obesity. Tirzepatide has the molecular formula C 22 H 348 N 48 O 68 (see Drug Summary Box). Figure 2 Amino acid sequence of tirzepatide in comparison to native GIP, GLP-1, and exendin-4 (exenatide). We’ve created a peptide dosage calculator to help you reconstitute your peptides fresh from the source, and then a peptide dosage chart with some common guidelines on dosing, timing, and injection site with all our sources and citations. Almost 90% of participants taking tirzepatide achieved an A1C below 7% . And many other peptides. The clinical efficacy of tirzepatide is superior to the GLP-1 RA dulaglutide. Along with diet and exercise, tirzepatide can lead to significant weight loss — up to 20%. SKU: TIRZ 10 Category: Trizepatide. 99 each and save 18%. INFORMATION. 2. The 15−2 mg tirzepatide dose-escalation regimens were 2. For this product you will need: BACTERIOSTATIC WATER For reconstitution. Subscribe for new products, updates and discounts. This medicine is available only with your doctor's prescription. Tirzepatide is a Synthetic Derivative of The Gastric Inhibitory Polypeptide (GIP) that also has simultaneous Glucagon-Like Peptide-1 (GLP-1) functionality. Previous product. 5mg once a week. Tirzepatide should not be used with other other GLP-1 receptor agonist medicines. Participants received subcutaneous injections of Tirzepatide or placebo once a week for 72 weeks. The meds in question are the dual GIP/GLP-1 agonist tirzepatide, a Type 2 diabetes candidate with ambitions to break into obesity, and donanemab, the anti-amyloid antibody that may soon run up. November 08, 2023. In SURMOUNT-3, those on tirzepatide lost an additional 21.